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October 9, 2018Cell Death and DiseaseOpen Access

Alpha-fetoprotein inhibits autophagy to promote malignant behaviour in hepatocellular carcinoma cells by activating PI3K/AKT/mTOR signalling

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Authors

SWShanshan WangMZMingyue ZhuQWQiaoyun Wang

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Wang et al. (2018) studied this question.

synapsesocial.com/papers/6a998769f8ae396fbf28f021https://doi.org/10.1038/s41419-018-1036-5
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Autophagy and apoptosis in liver injury2015 · 373 citations
  2. 2Hepatitis B virus X protein induces expression of alpha-fetoprotein and activates PI3K/mTOR signaling pathway in liver cells2015 · 76 citations
  3. 3Biomarkers: Evaluation of Screening for and Early Diagnosis of Hepatocellular Carcinoma in Japan and China2013 · 105 citations
  4. 4PTEN, more than the AKT pathway2007 · 404 citations
  5. 5Alpha fetoprotein mediates <scp>HB</scp>x induced carcinogenesis in the hepatocyte cytoplasm2015 · 57 citations