Answers are grounded in this paper and cite their sources.
Naturally occurring noncytotoxic vacA type s2 strains of Helicobacter pylori have a 12-residue extension to the vacuolating cytotoxin (VacA) compared with cytotoxic type s1 strains. We show that adding the region encoding this extension to type s1 vacA completely abolishes vacuolating cytotoxin activity but has no effect on VacA production.
No takes yet. Share an insight, caveat, or question.
Letley et al. (2000) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: