Why the study?
Does digoxin improve left atrial function in patients with congestive heart failure and dilated left atria?
Population
60 participants total: 30 patients with congestive heart failure and enlarged left atrium, and 30 normal…
Comparison
Digoxin 0.25 mg orally for 12 days. vs Baseline measurements and 30 normal participants…
Design
Cohort
Follow-up
12 days
Authors
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Digoxin may enhance left atrial function in HF; observational data leaves open need for randomized outcome trials.
Does digoxin improve left atrial function in patients with congestive heart failure and dilated left atria?
Digoxin significantly improves left atrial performance and contractility in both normal and failing dilated atria, with a more pronounced effect in patients with heart failure.
John Dernellis (2003) studied this question.
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