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December 23, 2003European Journal of Cardio-Thoracic SurgeryOpen Access

Supraventricular tachyarrythmia prophylaxis after coronary artery surgery in chronic obstructive pulmonary disease patients (early amiodarone prophylaxis trial)

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Why the study?

Does early amiodarone prophylaxis reduce supraventricular tachyarrhythmias in COPD patients undergoing coronary artery bypass grafting?

Population

300 patients with chronic obstructive pulmonary disease undergoing coronary artery bypass grafting. Group 1…

Comparison

Amiodarone prophylaxis in the early… vs No supraventricular tachyarrhythmia prophylaxis

Design

Cohort

Follow-up

hospital stay

Authors

EKErkan KuralayÇankaya University

Discussion

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Implication

May support amiodarone prophylaxis to reduce SVT in COPD patients after CABG; hypothesis-generating pending randomized confirmation.

Structured PICO

Does early amiodarone prophylaxis reduce supraventricular tachyarrhythmias in COPD patients undergoing coronary artery bypass grafting?

P
Population
300 patients with chronic obstructive pulmonary disease (COPD) undergoing coronary artery bypass grafting. Group 1 (n=200) had preoperative FEV1 <75% of predicted value, and Group 2 (n=100) had FEV1 >=75% of predicted value.
I
Intervention
Amiodarone prophylaxis in the early postoperative period
C
Comparator
No supraventricular tachyarrhythmia (SVT) prophylaxis
O
Outcome
Development of supraventricular tachyarrhythmias (including atrial fibrillation, atrial flutter, and multifocal atrial tachycardia)hard clinical

Early prophylactic amiodarone significantly reduces the incidence of supraventricular tachyarrhythmias and shortens ICU and hospital stays in COPD patients undergoing coronary artery bypass grafting.

Cite This Study

Erkan Kuralay (2003) studied this question.

synapsesocial.com/papers/6a999463ec7e3044fd56c81ehttps://doi.org/10.1016/j.ejcts.2003.11.006
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