A combination of either ruthenium(II) or rhodium(II) complexes and quinine‐derived squaramide enables 3‐diazooxindoles, indoles, and nitroalkenes to undergo highly efficient asymmetric three‐component reactions, thus affording optically active 3,3′‐bis(indole)s through a consecutive CC bond‐forming sequence, which turned out to be applicable to the facile total synthesis of (−)‐folicanthine.
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Chen et al. (2014) studied this question.
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