Transmission Ratios at the T-Locus in the Mouse: Inter-and Intra-Male Heterogeneity

Forty-nine litter series sired by TtO, Ttl, Pt3, Tt9, Tt12, and TtP' males of the house mouse were examined for heterogeneity of the transmission ratios of the l-allele. It was found that heterogeneity often I3xists, not only between males with the same t-allele, but even between litters from the same male; the latter was demonstrated by means of a new statistical technique. To measure the degree of heterogeneity, the mean square contingency was used as an index. It was found that intra-male heterogeneity was generally lower with "late" mating than with "normal" mating.