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June 1, 2018Cleveland Clinic Journal of Medicine

Thoracic aortic aneurysm: How to counsel, when to refer

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Population

Patients with thoracic aortic aneurysm, including those with bicuspid aortic valve, Marfan syndrome…

Design

Review

Key result

Thoracic aortic aneurysm management relies on size-based imaging surveillance, strict blood pressure control, and timely surgical referral, particularly in patients with genetic syndromes.

Authors

FCFrank CikachMDMilind Y. DesaiEREric E. Roselli

Discussion

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Overview

Supports size-based TAA surveillance and referral; leaves open RCTs to refine thresholds by etiology.

Structured PICO

P
Population
Patients with thoracic aortic aneurysm (TAA), including those with bicuspid aortic valve, Marfan syndrome, Loeys-Dietz syndrome, Ehlers-Danlos syndrome, and familial associations.
I
Intervention
Screening, medical management (beta-blockers, ACE inhibitors, or ARBs), activity restriction, imaging surveillance, and timely surgical referral.

Early detection, stringent blood pressure control, activity modification, and timely surgical referral based on size thresholds and genetic etiology are key to managing thoracic aortic aneurysms and preventing dissection or rupture.

Limitations

  • True incidence is difficult to determine as most cases are clinically silent until an acute event occurs.

Cite This Study

Cikach et al. (2018) conducted a review in Thoracic aortic aneurysm. Screening, monitoring, and management was evaluated. Thoracic aortic aneurysm management relies on size-based imaging surveillance, strict blood pressure control, and timely surgical referral, particularly in patients with genetic syndromes.

synapsesocial.com/papers/6a99a080ee60764e37aac6a4https://doi.org/10.3949/ccjm.85a.17039
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