Multisubstituted spiro trans -decalinol scaffolds can be synthesized using readily accessible cyclohexanone and β-nitrostyrene with 2-arylidene-1,3-indanedione with a good yield (up to 75%) and high diastereoselectivity (>20 : 1) via (2+2+2) cyclization.
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Settipalli et al. (2022) studied this question.
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