Liver transplantation is frequently performed these days; it is becoming an accepted therapeutic method and its success rate is increasing. A good deal of immunologic and metabolic information has become available by serendipity or through carefully planned experimental protocols in patients with liver transplants. Some of the most exciting results have been obtained in patients with inborn errors of metabolism involving the liver. Replacement of a liver that may be anatomically normal has been employed in the treatment of damage to extrahepatic organ systems — e.g., placement of a new heart and liver has been used to treat homozygous familial . . .
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Najarian et al. (1984) studied this question.
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