was incorrect.The correct table is: Table 1 AAN evidence classification scheme for a therapeutic articleClass I: Prospective, randomized, controlled clinical trial with masked outcome assessment, in a representative population.The following are required: a) Primary outcome(s) is/are clearly defined.b) Exclusion/inclusion criteria are clearly defined.c) Adequate accounting for drop-outs and crossovers with numbers sufficiently low to have minimal potential for bias.d) Relevant baseline characteristics are presented and substantially equivalent among treatments groups or there is appropriate statistical adjustment for differences.Class II: Prospective matched group cohort study in a representative population with masked outcome assessment that meets a-d above OR a randomized, controlled trial in a representative population that lacks one criteria a-d.Class III: All other controlled trials (including well-defined natural history controls or patients serving as own controls) in a representative population, where outcome assessment is independent of patient treatment.Class IV: Evidence from uncontrolled studies, case series, case reports, or expert opinion.
No takes yet. Share an insight, caveat, or question.
A 2003 study studied this question.