Walden Inversion of Amino Acids. VII. The Formation of N-p-Toluenesulfonylproline from Nδ-p-Toluenesulfonylornithine

Abstract (i) Kapfhammer and Eck’s report touching the synthesis of N-p-toluenesulfonyl-l-proline was corrected. (ii) N-p-Toluenesulfonylproline was resulted by the amination and methylamination of [l]-δ-p-toluenesulfonylamino-α- bromovaleric acid. In this case, racemization took place in consequence of amination at 100°, and partial Walden inversions were caused by amination at 0° and methylamination at 0° and 100°.