Why the study?
This study aimed to determine the circulating rotavirus genotypes among children 0 to 59 months with acute gastroenteritis in Zaria, Northwestern Nigeria.
Population
415 stool samples of children 0 to 59 months with acute gastroenteritis in Zaria, Northwestern Nigeria
Design
Cross-sectional hospital-based study
Key result
Rotavirus was detected in 12.3% of children aged 0-59 months with acute gastroenteritis, revealing a high diversity of genotypes including G1P[8], G12P[8], and G3P[6] (9.8% each).
Authors
Loading...
May warrant enhanced rotavirus surveillance in Nigeria; leaves open whether genotype diversity compromises vaccine effectiveness.
Cross-Sectional (n=415)
Yes
The study identified a high diversity of rotavirus strains, including unusual genotypes and mixed infections, in children with acute gastroenteritis in Northwestern Nigeria, which may impact vaccine effectiveness.
Giwa et al. (2021) conducted a cross-sectional in acute gastroenteritis (n=415). Rotavirus infection was evaluated on Rotavirus positivity and genotype distribution. Rotavirus was detected in 12.3% of children aged 0-59 months with acute gastroenteritis, revealing a high diversity of genotypes including G1P[8], G12P[8], and G3P[6] (9.8% each).