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May 1, 2012Expert Review of Clinical ImmunologyOpen Access

Stability of T-cell lineages in autoimmune diseases

Itay Raphael Thomas G. Forsthuber

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Abstract

Life is about change and instability – so should we be surprised that our favorite T-cell lineages are not as stable as we desperately hoped they would be? Probably not, and as much as this complic...

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Cite This Study

Raphael et al. (2012) studied this question.

synapsesocial.com/papers/6a99b904cc1ba4c2647b8a27 https://doi.org/10.1586/eci.12.22

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins.1986 · 7,506 citations
2Myelin Basic Protein–specific T Helper 2 (Th2) Cells Cause Experimental Autoimmune Encephalomyelitis in Immunodeficient Hosts Rather than Protect Them from the DiseaseOriginal Research · 1997 · 426 citations
3Th1, Th2, and Th17 Effector T Cell-Induced Autoimmune Gastritis Differs in Pathological Pattern and in Susceptibility to Suppression by Regulatory T CellsOriginal Research · 2008 · 170 citations
4Stability of Naive and Memory Phenotypes on Resting CD4 T Cells In VivoOriginal Research · 1999 · 36 citations
5Roles of IL-4 and IFN-gamma in stabilizing the T helper cell type 1 and 2 phenotypeOriginal Research · 1997 · 128 citations

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