New proton‐ionizable macrocyclic polyether ligands containing the 4‐pyridone subcyclic unit have been prepared by reacting 4‐THP blocked‐2,6‐pyridinedimethanol with various oligoethylene glycol ditosylates. The 18‐crown‐6 ligand containing the 4‐pyridone subcyclic unit, 4, forms stable complexes with alkali metal and organic ammonium cations. The crystal structure of 4 proves the 4‐pyridone structural unit. The crystal structure of the potassium thiocyanate complex of 4 is also reported and shows the complex to contain the 4‐hydroxypyridine unit.
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Bradshaw et al. (1986) studied this question.
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