Letters15 April 1997POEMs: Patient-Oriented Evidence That MattersAllen F. Shaughnessy, PharmD and David C. Slawson, MDAllen F. Shaughnessy, PharmDHarrisburg Family Practice Residency, Harrisburg, PA 17105University of Virginia, Charlottesville, VA 22908 and David C. Slawson, MDHarrisburg Family Practice Residency, Harrisburg, PA 17105University of Virginia, Charlottesville, VA 22908Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-126-8-199704150-00032 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:Fleming and DeMets [1] do an excellent job of pointing out the inadequacy of surrogate markers as appropriate outcomes for phase III trials. Surrogate markers are also inappropriate for clinical practice, yet they serve as the foundation on which many of the daily decisions in medicine are made.Managed care is forcing clinicians to re-evaluate their decision making with well-focused questions on outcomes of care. Many clinicians try to deflect these queries as merely being based on finances. These questions, however, force us to examine our practices to determine whether our interventions truly are in the best ...References1. Fleming TR, DeMets DL. Surrogate end points in clinical trials: are we being misled? Ann Intern Med. 1996; 125:605-13. Google Scholar2. Slawson DC, Shaughnessy AF, Bennett JH. Becoming a medical information master: feeling good about not knowing everything. J Fam Pract. 1994; 38:505-13. Google Scholar3. Riffenburgh RH. Reverse gullibility and scientific evidence. Arch Otolaryngol Head Neck Surg. 1996; 122:600-1. Google Scholar Author, Article, and Disclosure InformationAffiliations: Harrisburg Family Practice Residency, Harrisburg, PA 17105University of Virginia, Charlottesville, VA 22908 PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byTesting polyp resection techniques: Are we asking the clinically relevant questions?Quality and Outcome Measures for Medical RehabilitationQuality and Outcome Measures for Medical RehabilitationCommunicating statin evidence to support shared decision-makingSufficiently Important DifferenceEmerging Concepts in the Treatment of Myofascial Pain: A Review of Medications, Modalities, and Needle-based InterventionsUse of a fermented dairy probiotic drink containing Lactobacillus casei (DN-114 001) to decrease the rate of illness in kids: the DRINK study A patient-oriented, double-blind, cluster-randomized, placebo-controlled, clinical trialReihe Evidenzbasierte Chirurgie 15 April 1997Volume 126, Issue 8Page: 667KeywordsBiomarkersClinical trialsDecision makingPatients Issue Published: 15 April 1997 Copyright & PermissionsCopyright © 1997 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...
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