Key result
Conservative treatment successfully reduced a life-threatening serum potassium level of 10.2 mmol/L to 4.6 mmol/L within 18 hours in a diabetic patient with severe hyperglycemia.
Why the study?
Hyperkalemia is a life-threatening condition potentially leading to cardiac arrest, presenting here as a case of severe hyperkalemia of 10.2 mmol/L treated conservatively.
Case Report (n=1)
No
Severe hyperkalemia of 10.2 mmol/L can be successfully managed conservatively without dialysis in a patient with concurrent hyperglycemia, which may offer cardioprotective effects via hyperosmolality.
May support avoiding dialysis for severe hyperkalemia with hyperglycemia; leaves open generalizability beyond this case.
Hyperkalemia is a life-threatening condition potentially leading to cardiac arrest. Here, we report a case of surprising severe hyperkalemia of 10.2 mmol/L in a diabetic patient with previously normal kidney function presenting without discernible clinical symptoms to our emergency department. The patient was admitted because of hyperglycemia of 32.8 mmol/L, which was detected during daily testing in her nursing home. The hyperkalemia was caused by prerenal failure due to hyperglycemic polyuria which led to volume depletion, and worsened by a combination of potassium-sparing drugs and potassium supplementation. The patient was treated conservatively. Eighteen hours later, the serum potassium concentration was 4.6 mmol/L. The patient could be released 6 days later. To our knowledge, this is the highest described hyperkalemia treated conservatively and survived without cardiopulmonary resuscitation.
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Czogalla et al. (2021) conducted a case report in Hyperkalemia and Hyperglycemia (n=1). Conservative treatment (isotonic saline, furosemide, sodium bicarbonate, calcium gluconate, insulin) was evaluated on Serum potassium concentration. Conservative treatment successfully reduced a life-threatening serum potassium level of 10.2 mmol/L to 4.6 mmol/L within 18 hours in a diabetic patient with severe hyperglycemia.
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