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5-Endo-dig iodocyclisations of alk-3-yn-1,2-diols 4, followed by in situ dehydration, lead to good yields of β-iodofurans 5, which can subsequently be converted into a wide range of derivatives 6-13, using transition metal-catalysed coupling reactions or halogen-metal exchange.
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Bew et al. (1996) studied this question.
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