Pectin and the polysaccharide scleroglucan reduced dietary hypercholestero-lemia in chicks; this reduction was accompanied by an increased excretion of chloroform-methanol extractable lipid, including cholesterol. The chemical dissimilarity of pectin and scleroglucan suggests that the anti-hyper-cholesterolemic activity of the two materials may be due to their physical rather than to their chemical properties.
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Griminger et al. (1966) studied this question.