Inclusion Compounds of Diol Hosts Featuring Two 9-Hydroxy-9-fluorenyl or Analogous Groups Attached to Linear Spacer Units

A series of new clathrate host molecules 1−15, each containing two 9-hydroxy-9-fluorenyl or analogous terminal groups attached to linear central units of different lengths and structural compositions, has been synthesized. Their crystalline inclusion compounds with a variety of organic guests − including amines, alcohols, ketones, and other dipolar aprotic compounds or aromatic hydrocarbons − are reported (229 examples of clathrates) and their properties are compared. The crystal structures of a free host compound and of six selected clathrates of different compound classes have been determined by X-ray diffraction, showing varied modes of supramolecular interaction.