Diagnostic study demonstrates 82.2% sensitivity for detecting urinary protein biomarkers in visceral leishmaniasis patients, indicating strong potential for noninvasive diagnostics.
, respectively. In contrast, a multiplexed assay designed to simultaneously detect all five leishmanial biomarkers markedly increased the assay sensitivity to 82.2%. These results validate the utility of leishmanial protein biomarkers found in the urine of VL patients as powerful tools for the development of an accurate diagnostic test for this disease.
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Abeijón et al. (2019) studied this question.
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