Vitamin C acts as a powerful radical scavenger, and can be used as a convenient antioxidant agent in aqueous media. To extend its properties to nonaqueous environments, alkanoyl-6-O-ascorbic acid esters with different chain lengths were synthesized, and their micellar and antioxidant properties were investigated by surface tension, viscosity, light scattering, neutron scattering, oxygen uptake, and UV/VIS spectra. According to our results, octanoyl-ascorbic acid forms nearly spherical micelles in water solutions above a cmc of about 6 × 10 - 3 mol/L at 30 °C, while decanoyl- and dodecanoyl-ascorbic acid are poorly soluble in water. No matter how long the hydrophobic chain is, all these esters show the same antioxidant activity as vitamin C and other natural products.
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Nostro et al. (1999) studied this question.
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