A patient with clinically diagnosed Stage I primary idiopathic osteoarthritis of the first metacarpal trapezium joint of the left hand received intra-articular administration of dexamethasone acetate. Compared to pretreatment T2- weighted MR images, greatly decreased MR signal intensity was observed in the affected joint space and adjacent soft tissues 2 days after dexamethasone acetate therapy. This was representative of reduced edema in the metacarpal trapezium joint and demonstrated the ability of MRI to follow pharmacological treatment for arthritis.
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Tankhiwale et al. (1995) studied this question.
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