Key result
Previous ischemic stroke predicted postoperative myocardial injury after carotid endarterectomy (OR 4.1; 95% CI 1.1-16.1; P=.04), as did abnormal ST-segment changes (OR 5.9; 95% CI 1.3-27.7; P=.04).
Observational (n=40)
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Previous ischemic stroke and abnormal ST-segment changes are significant predictors of myocardial injury following carotid endarterectomy in patients with symptomatic severe carotid stenosis.
Myocardial injury following carotid endarterectomy (CEA) is a common cause of morbidity and mortality, and its risk varies depending on the severity and extent of disease. However, when patients with sympotomatic severe carotid stenosis undergo CEA, the frequency and potential predictors of myocardial injury remain unknown. A total of 40 patients (32 men and 8 women) who underwent successful standard CEA were observed. Cardiac troponin I (cTnI) concentrations were assessed before surgery and on postoperative days 1, 2, and 3 in all patients. Myocardial injury was defined as the peak cTnI concentration > 0.04 ng/mL. In all, 42.5% patients had postoperative myocardial injury. Previous ischemic stroke and abnormal ST-segment changes were the preoperative predictors of myocardial injury after CEA, with odds ratios of 4.1 (95% confidence interval, 1.1-16.1; P = .04) and 5.9 (95% confidence interval, 1.3-27.7; P = .04), respectively. Sympotomatic patients with those conditions should receive more attention to myocardial injury, when presented for CEA.
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Feng et al. (2013) conducted an observational in Symptomatic severe carotid artery stenosis (n=40). Previous ischemic stroke vs. No previous ischemic stroke was evaluated on Postoperative myocardial injury (peak cTnI > 0.04 ng/mL) (OR 4.1, 95% CI 1.1-16.1, p=.04). Previous ischemic stroke predicted postoperative myocardial injury after carotid endarterectomy (OR 4.1; 95% CI 1.1-16.1; P=.04), as did abnormal ST-segment changes (OR 5.9; 95% CI 1.3-27.7; P=.04).
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