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June 6, 1994Angewandte Chemie International Edition in English

Regio‐ and Enantioselective Silane‐Terminated Intramolecular Heck Reactions

Lutz F. Tietze Ralph Schimpf

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Abstract

The selective formation of tertiary sp3 centers is possible when allylsilanes 1 are employed as the alkene component in the title reaction. Application of a chiral catalyst system makes the reaction enantioselective. Primarily hetero- and carbo-cycles 2 arise with the catalyst system [Pd2(dba)3/PPh3/Ag2O]; 3 is the main product with Pd(OAc2)/PPh3/NPr4Br/KOAc.

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Cite This Study

Tietze et al. (1994) studied this question.

synapsesocial.com/papers/6a99dfff82cc6f575b1d76b5 https://doi.org/10.1002/anie.199410891

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