THE development of bony and tissue changes in patients with acromegaly is so insidious that the victims of this disorder as a rule seek medical assistance only in its advanced stages. Very little can then be accomplished in the correction of these effects. On the other hand, satisfactory treatment of acromegaly is usually possible providing the condition is recognized early, and if energetic attempts are made to follow patients with this malady at regular intervals. The unpredictable course of acromegaly, however, renders evaluation of treatment difficult in some cases. This review of our experience in the management of acromegaly was undertaken to evaluate past treatment with the hope of possible improvement in the future. The first objective of treatment is the relief of symptoms resulting from the expanding tumor, if such exists, which may cause headache and visual or other neurologic disturbances. Many patients with acromegaly are not affected in this way, so that the question of treatment of secondar...
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Hurxthal et al. (1949) studied this question.