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The title compound, a promising antiviral carbocyclic nucleoside analogue, was synthesized enantiospecifically. The present synthesis involves a coupling reaction of 5-amino-4,6-dichloropyrimidine and (1R,2R,3R,4R)-2,3-dihydroxy-4-(hydroxymethyl)cyclopentanamine which was in turn prepared from d-xylose.
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Tadano et al. (1989) studied this question.
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