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February 19, 2002Statistics in Medicine

Comparing results of large clinical trials to those of meta‐analyses

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Authors

LMLincoln E. MosesUniversity of North Carolina at Chapel HillFMFrederick MostellerBoston UniversityJBJohn BuehlerHarvard University Press

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Moses et al. (2002) studied this question.

synapsesocial.com/papers/6a99efcdf7bc4aca2e45a93chttps://doi.org/10.1002/sim.1098
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Also Consider

Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Large Trials vs Meta-analysis of Smaller Trials1996 · 348 citations
  2. 2Discrepancies between Meta-Analyses and Subsequent Large Randomized, Controlled Trials1997 · 1,185 citations
  3. 3Issues in Comparisons Between Meta-analyses and Large Trials1998 · 255 citations