Concerning possible aetiological rela- tionships, it is to be noted that seven cases of angiosarcoma (malignant hae- mangioendothelioma) of the liver have been diagnosed among individuals em- ployed at a local vinyl chloride polymerization plant.The first case was diagnosed in April 1964, and two recent cases in February 1974.Four additional cases of liver fibrosis with sinusoidal cell activity have been documented histologically.All individuals had close and prolonged contact with the vinyl chloride polymerization process.
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A 1974 study studied this question.