Review highlights the theranostic potential of the Eph/ephrin signaling system in human physiology and pathology, indicating key avenues for developing targeted disease therapies.
Comprehensive basic biological knowledge of the Eph/ephrin system in the physiologic setting is needed to facilitate an understanding of its role and the effects of pathological processes on its activity, thereby paving the way for development of prospective therapeutic targets. To this end, this review briefly addresses what is currently known and being investigated in order to highlight the gaps and possible avenues for further investigation to capitalize on their diverse potential.
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Hughes et al. (2020) studied this question.
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