Key result
Mild smoking (<20 cigarettes per day) was associated with significantly lower small artery elasticity compared to non-smokers (6.52 vs 7.36; p=0.048).
Why the study?
Does mild smoking reduce arterial elasticity in healthy adults compared to non-smokers?
Cross-Sectional
Yes
Does mild smoking reduce arterial elasticity in healthy adults compared to non-smokers?
Absolute Event Rate: 6.52% vs 7.36%
p-value: p=0.048
Even modest smoking of a few cigarettes per day is associated with significantly reduced small artery elasticity in healthy adults.
Even mild smoking merits clinical attention for vascular effects; leaves open causality and prognostic value pending prospective data.
The purpose of the present study was to estimate non-invasively, arterial elasticity parameters using the HDI/PulseWave™ CR-2000 Cardiovascular Profiling System in healthy subjects according to smoking profile. We evaluated AE in healthy population, thus the subjects included wereeither non-smokers or smokers of less than 20 cigarettes per day. AE was evaluated in healthy European adults between the ages of 15 and 80 years with a BMI of less than 30 kg/m2. The subjects, recruited at work sites were required to complete an Assessment Profile Questionnaire that queried health history and medications. All subjects signed an Informed Consent Form. Small artery elasticity (SAE) was significantly higher in non-smokers than in mild smokers (7.36+/−2.59 vs 6.52+/−2.43, p=0.048). Large artery elasticity (LAE) was of borderline significance (15.93+/−4.19 vs 14.92+/−2.98, p=0.05). Analysis for smoking dose revealed the following parameters significantly correlated to smoking dose: SAE (r= −0.113, p=0.0048), estimated SV (r= −0.149, p=0.009), estimated CO (r= −0.143, p=0.012). We conclude that AE in modest smokers of a few cigarettes per day is lower than in non-smokers.
No takes yet. Share an insight, caveat, or question.
R ZIMLICHMAN (2003) conducted a cross-sectional in Healthy subjects. Mild smoking (<20 cigarettes per day) vs. Non-smokers was evaluated on Small artery elasticity (SAE) (p=0.048). Mild smoking (<20 cigarettes per day) was associated with significantly lower small artery elasticity compared to non-smokers (6.52 vs 7.36; p=0.048).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: