Ever since the early discoveries that highly oxidized transition-metal reagents are able to react with olefins to form oxidized organic compounds, chemists have investigated and developed novel methods for selective oxidations. The major breakthrough by Sharpless in the 1980s in discovering the osmium-catalyzed asymmetric dihydroxylation (AD) of olefins has inspired numerous researchers, and as a result this particular scientific area is currently thoroughly investigated. Nevertheless, new developments of this highly useful reaction are still being made. The intent of this review is to highlight recent developments achieved in asymmetric dihydroxylations with regards to improvement of the catalytic systems and extension of the substrate scope.
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Adolfsson et al. (2006) studied this question.
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