Amphotericin B and platelet transfusion

Platelet transfusions are being prescribed with everincreasing frequency, yet the response in recipients is not optimal. On the basis of generally accepted physiologic principles, it can be estimated' that the transfusion of 1 unit (7.5 x 1O'O) of platelets should result in an increase in platelet count of 20,OOO per m3 in a recipient with 1 m2 body surface area. Thus, for each individual transfusion, one can calculate the corrected count increment (CCI)2