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A methyl methanesulfonate-sensitive strain has been isolated from L5178Y mouse lymphoma cells. This mutant, M10, is more sensitive to killing by X rays than the parent wild-type strain. This sensitivity to the alkylating agent and ionizing radiation has not changed for 11 months since the isolation of the mutant. The plating efficiency, doubling time, and sensitivity to ultraviolet light of M10 cells are not appreciably different from those of the wild-type cells.
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Sato et al. (1979) studied this question.
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