Key result
A 73-year-old man with recurrent embolic stroke of undetermined source was found to have lipomatous hypertrophy of the interatrial septum, highlighting a potential rare embolic etiology.
Case Report (n=1)
No
This case report highlights lipomatous hypertrophy of the interatrial septum (LHIS) as a rare, potential associated finding in patients with embolic stroke of undetermined source, emphasizing the role of multimodality cardiac imaging.
Lipomatous hypertrophy of interatrial septum (LHIS) is a rare benign cardiac mass. Most of LIHS is found incidentally during the examination because it does not cause symptoms. LHIS is sometimes reported to be accompanied with atrial fibrillation and various arrhythmia, but the exact mechanism of its occurrence are unknown. There is nothing known about the relationship between LHIS and ischemic stroke.LHIS is non-capsulated cardiac benign tumor formed by fat infiltration in the cardiac septum. The exact prevalence of LHIS is unknown but about 1% has been found in autopsies. In this case, the association between stroke and LHIS is not definite. But it is possible that LHIS led to undetected paroxysmal atrial fibrillation, possibly resulting in embolic stroke. Another possibility is that a blood clot was formed on the tumor surface. But this is only possible if there is a right to left shunt in the atrium. Shunt has not been identified in our patients. Further studies are needed to determine the association with stroke and LHIS.
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Bae et al. (2018) conducted a case report in Embolic stroke of undetermined source (ESUS) (n=1). Lipomatous hypertrophy of interatrial septum was evaluated. A 73-year-old man with recurrent embolic stroke of undetermined source was found to have lipomatous hypertrophy of the interatrial septum, highlighting a potential rare embolic etiology.
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