Serum Protein Electrophoresis Patterns in Acrylamide Gel: Patterns from Normal and Bursaless Birds ,

REMOVAL of the bursa of Fabricius, a lympho-epithelial gland, from the chicken will markedly interfere with the production of circulating antibody (Glick et al., 1956; and Warner and Szenberg, 1964). Bursaless birds may be hatched by dipping eggs in ethyl alcohol solutions containing more than 1.28 gm. percent of testosterone propionate (Glick, 1964) or by injecting TP or 19 — Nortestosterone into the fertile egg (Warner and Szenberg, 1964). These chemically bursectomized birds are deficient antibody producers. The characterization of the serum proteins of chemically bursectomized and normal birds was undertaken in this laboratory utilizing a 7% acrylamide gel (Glick, 1967). This manuscript will: (1) present the electropherograms for 3 and 5 week old birds, 2) compare the relative mobilities of the different serum proteins of hormonally bursectomized and normal birds, 3) tentatively identify 8 of the 19 serum protein bands, and 4) offer data suggesting that chemically bursectomized birds contain . . .