Tough shell: Living yeast cells can be simultaneously silica-encapsulated and thiol-functionalized by polycondensation of silicic acid and (3-mercaptopropyl)trimethoxysilane under mild conditions. Various functions such as fluorescent dyes (see picture; green: fluorescein, red: rhodamine), chemical moieties, or proteins, can be introduced to the artificial shell by using maleimide-based coupling reactions.
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Yang et al. (2011) studied this question.
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