Nitrosourea derivatives 9--13 which utilize phensuximide (1) as the carrier were synthesized as potential central nervous system antitumor agents. The N-(2-chloroethyl)-N-nitrosourea 13 was active in the mouse ependymoblastoma brain-tumor system, as well as the intraperitoneal L1210 leukemia system.
No takes yet. Share an insight, caveat, or question.
Crider et al. (1980) studied this question.
Synapse has enriched 5 related papers. Consider them for comparative context: