Key result
The filtered dynamic time warping-based averaging scheme increased P200 median peak and amplitude by 26.44% and 29.30%, respectively, compared to conventional averaging, while reducing root-mean-square deviation.
Why the study?
Variability in latency jitter and amplitude across trials and users causes average event-related potential waveforms to blur and diminishes the amplitude of underlying waves.
A dynamic time warping strategy improves the quality of averaged event-related potential waveforms in EEG analysis by reducing latency and jitter variability.
Electroencephalography (EEG) provides a way to understand, and evaluate neurotransmission. In this context, time-locked EEG activity or event-related potentials (ERPs) are often used to capture neural activity related to specific mental processes. Normally, they are considered on the basis of averages across a number of trials. However, there exist notable variability in latency jitter, jitter, and amplitude, across trials, and, also, across users; this causes the average ERP waveform to blur, and, furthermore, diminish the amplitude of underlying waves. For these reasons, a strategy is proposed for obtaining ERP waveforms based on dynamic time warping (DTW) to adapt, and adjust individual trials to the averaged ERP, previously calculated, to build an enhanced average by making use of these warped signals. At the sight of the experiments carried out on the behaviour of the proposed scheme using publicly available datasets, this strategy reduces the attenuation in amplitude of ERP components thanks to the reduction of the influence of variability of latency and jitter, and, thus, improves the averaged ERP waveforms.
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Molina et al. (2023) studied Healthy subjects and Amyotrophic Lateral Sclerosis (ALS) (n=26). Filtered dynamic time warping (DTW)-based averaging vs. Conventional synchronous averaging was evaluated on Root-mean-square (RMS) deviation and maximum absolute difference (MAD) between individual trials and averaged ERP signals. The filtered dynamic time warping-based averaging scheme increased P200 median peak and amplitude by 26.44% and 29.30%, respectively, compared to conventional averaging, while reducing root-mean-square deviation.
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