Key result
Prolonged signal-averaged P wave duration above 160 ms after elective cardioversion significantly increased the risk of recurrent atrial fibrillation at 1 month (OR 2.22; 95% CI 1.07-4.60; p=0.03).
Why the study?
Does prolonged signal-averaged P wave duration (>160 ms) predict recurrent atrial fibrillation in patients after elective cardioversion?
Cohort (n=131)
Does prolonged signal-averaged P wave duration (>160 ms) predict recurrent atrial fibrillation in patients after elective cardioversion?
Prolonged signal-averaged P wave duration (>160 ms) is a significant independent predictor of early atrial fibrillation recurrence following elective cardioversion.
May inform post-cardioversion AF recurrence risk; hypothesis-generating and requires prospective validation before clinical use.
OBJECTIVE: To assess the risk of atrial fibrillation (AF) recurrence after elective cardioversion of AF in relation to the signal-averaged P wave duration (SAPWD), clinical characteristics of the patient, and the duration of the AF disease. DESIGN: We studied 131 consecutive patients (88 men, 43 women), median age 67 years (range 29-87 years), after elective cardioversion of AF into sinus rhythm. The SAPWD was measured on inclusion, and the follow-up period was 1 month. Recurrent AF within the first month after cardioversion was regarded as endpoint. RESULTS: AF recurred in 73 patients (56%). Multiple logistic regression analysis showed that prolonged SAPWD above 160 ms was the only significant risk factor for recurrent AF, OR=2.22 (95% CI 1.07-4.60), p=0.03. There was no significant effect of age, diagnosed hypertension, diagnosed congestive heart failure, dilated left atrium, or long duration of AF on the risk of AF relapse. CONCLUSION: Prolonged SAPWD above 160 ms is a risk factor for recurrent AF after elective cardioversion of persistent AF.
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Dixen et al. (2004) conducted a cohort in Atrial fibrillation after elective cardioversion (n=131). Prolonged signal-averaged P wave duration above 160 ms vs. Signal-averaged P wave duration ≤160 ms was evaluated on Recurrent atrial fibrillation within the first month after cardioversion (OR 2.22, 95% CI 1.07-4.60, p=0.03). Prolonged signal-averaged P wave duration above 160 ms after elective cardioversion significantly increased the risk of recurrent atrial fibrillation at 1 month (OR 2.22; 95% CI 1.07-4.60; p=0.03).
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