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cytotoxicity examined using Vero cell cultures, the as-prepared HAP particles exhibit excellent cytocompatibility and cell viability as high as 83% at an extract concentration as low as 25%. Moreover, the loading and leaching behavior of the drug in mesoporous HAP was studied using methionine (MT), an essential amino acid. These results confirm that nano mesoporous hydroxyapatite loaded with MT can be a potential aspirant as a biomaterial in biomedical applications.
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Lett et al. (2019) studied this question.
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