Key result
A 60-year-old female with stage IVB cervical squamous cell carcinoma developed fatal pulmonary tumor embolism, confirmed by autopsy showing diffuse tumor emboli in bilateral pulmonary arteries.
Case Report (n=1)
Pulmonary tumor embolism should be considered in patients with malignant disease who develop unexplained dyspnea, hypoxemia, and pulmonary hypertension.
May alert clinicians to tumor embolism in cervical cancer patients with acute dyspnea and RV strain; leaves open questions on incidence and management.
BACKGROUND/AIM: We report on a case of pulmonary tumor embolism caused by squamous cell carcinoma of the uterine cervix. PATIENTS AND METHODS: A 60-year-old female diagnosed with stage IVB (cT4N1M1) squamous cell carcinoma of the uterine cervix was admitted to our institution with a chief complaint of progressive dyspnea that developed within a few days after admission. RESULTS: A chest CT scan showed dilated pulmonary arteries, right ventricular enlargement and mosaic ground-glass opacities in both lungs. An echocardiogram revealed elevated right ventricular pressure and a floppy mass in the right ventricle. Pulmonary tumor embolism was highly suspected. However, she died from respiratory failure on the fourth day after admission. Autopsy revealed diffuse tumor emboli in bilateral pulmonary arteries and arterioles. CONCLUSION: Pulmonary tumor embolism should be considered when patients with malignant disease develop unexplained dyspnea, hypoxemia, and pulmonary hypertension.
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Okazaki et al. (2018) conducted a case report in Pulmonary tumor embolism due to squamous cell carcinoma of the uterine cervix (n=1). Squamous cell carcinoma of the uterine cervix was evaluated on Death from respiratory failure and autopsy findings. A 60-year-old female with stage IVB cervical squamous cell carcinoma developed fatal pulmonary tumor embolism, confirmed by autopsy showing diffuse tumor emboli in bilateral pulmonary arteries.
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