Key result
Computed Tomography Angiography measurements of all four cardiac chambers in 226 normal patients correlated well with established normative values from echocardiography.
Why the study?
What are the normative values for four-chamber cardiac anatomy measured by Computed Tomography Angiography in patients without structural heart disease?
Observational (n=226)
No
What are the normative values for four-chamber cardiac anatomy measured by Computed Tomography Angiography in patients without structural heart disease?
This study provides initial normative reference values for four-chamber cardiac CTA measurements, demonstrating similarity to established echocardiographic norms.
CTA chamber norms align with echo in normals; extends reference data but remains hypothesis-generating for clinical adoption.
Background: Computed Tomography Angiography (CTA) is a new and promising type of imaging to evaluate cardiac structure and function. Although it does require injection of contrast material and some radiation exposure, it is much less invasive than conventional catheter based on angiography. It has been already shown to correlate well with echocardiography images, but normative values have yet to be established. Objectives: To publish the first known data on CTA measurements for all four chambers of the heart. Methods: We conducted a retrospective chart review study of around 3000 patients over a three-year period (2006-2008) from a private cardiology practice in Phoenix, Arizona. Patients were screened for any preexisting conditions that might contribute to abnormal cardiac structures. A “normal” population of 226 patients’ CTA’s was reviewed and 29 different measurements were taken cardiac anatomy. Patients were then categorized based on sex and BMI and the cardiac measurements were compared. Results: The values obtained were similar to already established normal measurement values from echocardiography. There was good correlation between body mass index (BMI) and the sexes. Conclusion: This study serves to establish normative data for cardiac CTA while also proves to show good correlation with already established normative values for echocardiography and justifies these CTA measurements as an alternative means of cardiac evaluation. Further study regarding the variations between data for specific measurements will be addressed in future studies.
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Whittington et al. (2014) conducted an observational in Normal cardiac anatomy (n=226). Computed Tomography Angiography (CTA) vs. Echocardiography was evaluated on Normative values for 29 different cardiac anatomy measurements. Computed Tomography Angiography measurements of all four cardiac chambers in 226 normal patients correlated well with established normative values from echocardiography.
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