Key result
Mitral valve repair is linked to ~16-point higher 10-year survival vs. replacement in older adults.
Why the study?
Despite the established superiority of mitral repair over replacement, robust long-term survival data in elderly patients were lacking, limiting uniform adoption.
Does primary isolated mitral valve repair improve long-term survival compared to replacement in patients ≥65 years of age?
Cohort (n=47,279)
Yes
Does primary isolated mitral valve repair improve long-term survival compared to replacement in patients ≥65 years of age?
Answers are grounded in this paper and cite their sources.
In elderly Medicare beneficiaries, mitral valve repair is associated with significantly lower operative mortality and better 10-year survival compared to replacement.
BACKGROUND: Despite the established superiority of mitral repair over replacement, its adoption in the treatment of elderly patients has not been uniform, partly because of a lack of robust long-term survival data. We present the long-term survival of Medicare fee-for-service beneficiaries undergoing mitral valve repair and replacement over a 10-year period. METHODS AND RESULTS: We used the Medicare database to identify 47 279 fee-for-service beneficiaries ≥65 years of age undergoing primary isolated mitral valve repair or replacement from 2000 to 2009. Operative mortality and long-term survival are presented for repair and replacement. Operative mortality was 3.9% for patients undergoing repair and 8.9% for patients undergoing replacement. The 1-, 5-, and 10-year Kaplan-Meier survival estimates for patients undergoing repair were 90.9%, 77.1%, and 53.6%. The 1-, 5-, and 10-year Kaplan-Meier survival estimates for patients undergoing replacement were 82.6%, 64.7%, and 37.2%. Important predictors of mitral repair included younger age (odds ratio, 1.10; 95% confidence interval, 1.05-1.14), elective admission status (odds ratio, 1.34; 95% confidence interval, 1.27-1.41), and annual mitral procedure volume >40 cases per year (odds ratio, 1.57; 95% confidence interval, 1.36-1.81). Female sex and the presence of comorbidities were associated with a lower likelihood of repair. CONCLUSIONS: Mitral valve surgery in the Medicare population carries less risk than previously reported. Given the favorable outcomes of elderly patients undergoing mitral valve surgery, especially mitral valve repair, an approach of earlier identification and surgical referral appears justified regardless of age.
No takes yet. Share an insight, caveat, or question.
Vassileva et al. (2013) conducted a cohort in Mitral valve disease requiring surgery (n=47,279). Mitral valve repair vs. Mitral valve replacement was evaluated on 10-year survival. In Medicare beneficiaries ≥65 years, mitral valve repair was associated with higher 10-year survival (53.6% vs 37.2%) and lower operative mortality (3.9% vs 8.9%) compared to replacement.
Synapse has enriched 10 related papers. Consider them for comparative context: