Key result
Pulse wave derived form factor analysis revealed significant differences between myocardial ischemia patients and healthy subjects, particularly at Cun and Guan points (p<0.01).
Why the study?
Does pulse wave derived form factor analysis differentiate patients with myocardial ischemia from healthy subjects and those with ischemia-like symptoms?
Cross-Sectional (n=63)
Does pulse wave derived form factor analysis differentiate patients with myocardial ischemia from healthy subjects and those with ischemia-like symptoms?
Pulse wave form factor analysis using three-axis sphygmography shows potential as an early screening tool for myocardial ischemia, though it currently struggles to differentiate true ischemia from ischemia-like symptoms.
Pulse wave form factor analysis may support ischemia screening; hypothesis-generating in case-control data and needs validation vs ischemia mimics.
Pulse wave analysis with computerized diagnosis was used for myocardial ischemia patients. Novel feature derived from form factor of pulse signal was investigated. Form factor is estimated from variance of pulse signal waveform. Pulse waves were measured using newly developed three-axis sphygmography. Three groups participated in this study: 16 patients diagnosed with myocardial ischemia (positive), 19 healthy subjects (control) and 28 subjects exhibiting myocardial ischemia-like symptoms (negative). Form factor distribution and pulse wave variations of the three groups were calculated. Six form factor values derived from both hands’ acupoints on Cun, Guan, and Chi were calculated. Data showed that there were significant statistical differences between myocardial ischemia patients and healthy subjects with respect to form factor, especially for Cun and Guan points (p<0.01). The negative group showed similar results to the myocardial ischemia patients. This study showed that form factor will be potential feature for pulse signal. It can be applied for the early screen of myocardial ischemia candidates by form factor features.
No takes yet. Share an insight, caveat, or question.
Kang-Ming Chang (2012) conducted a cross-sectional in Myocardial ischemia (n=63). Pulse wave derived form factor analysis vs. Healthy subjects and subjects with ischemia-like symptoms was evaluated on Form factor distribution and pulse wave variations (p=<0.01). Pulse wave derived form factor analysis revealed significant differences between myocardial ischemia patients and healthy subjects, particularly at Cun and Guan points (p<0.01).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: