Recent Advances in the Carbon–Carbon Bond-Forming Reactions of N-Acylketimines

N-Acylketimines are important synthetic building blocks used in the synthesis of a wide variety of functional amino compounds including cyclic and acyclic products. This review focuses on carbon–carbon bond-forming reactions of N-acylketimines to construct amino compounds having tetrasubstituted carbon centers. 1 Introduction 2 Preparation of N-Acylketimines 2.1 Nucleophilic Addition of Amide Derivatives 2.2 Acylation of Imine Derivatives 2.3 An Aza-Wittig-Type Reaction 2.4 Oxidation of Amine Precursors 3 Reactions of N-Acylketimines 3.1 Cyclic Ketimines 3.2 Acyclic Ketimines 4 Conclusions