Key result
Fasting plasma triglyceride levels rapidly increased on a 40% fat diet and rapidly decreased on a 10% fat diet in a 9-year-old girl with primary type V hyperlipoproteinemia.
Why the study?
Does a low-fat diet reduce fasting plasma triglyceride levels in a child with primary type V hyperlipoproteinemia?
Case Report (n=1)
Does a low-fat diet reduce fasting plasma triglyceride levels in a child with primary type V hyperlipoproteinemia?
Early diagnosis and prompt institution of a low-fat diet is important in childhood primary type V hyperlipoproteinemia to manage triglyceride levels and prevent acute pancreatitis.
Low-fat diet may aid triglyceride control in pediatric type V hyperlipoproteinemia; leaves open confirmation in prospective studies.
Metabolic studies of a 9-year-old girl with primary type V hyperlipoproteinemia demonstrated normal glucose tolerance, plasma insulin and glucagon responses to stimuli, and serum uric acid level. Fasting plasma triglyceride levels rapidly increased when the patient received a diet containing 40% of the total calories as fat and rapidly decreased on a 10% fat diet. Hepatic and nonhepatic lipase activities in postheparin plasma were normal, thus excluding type I hyperlipoproteinemia. Because of the potential complication of acute pancreatitis in this disorder, early diagnosis and prompt institution of diet therapy is important.
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Daniel Yeshurun (1977) conducted a case report in Primary type V hyperlipoproteinemia (n=1). Dietary fat modification vs. 10% fat diet was evaluated on Fasting plasma triglyceride levels. Fasting plasma triglyceride levels rapidly increased on a 40% fat diet and rapidly decreased on a 10% fat diet in a 9-year-old girl with primary type V hyperlipoproteinemia.
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