Two hepatitis C antibody assays were used to test diluted positive sera. Dilutions of 1 in 5, 1 in 10, and 1 in 20 all resulted in loss of reactivity, with the greatest losses occurring in samples with low and moderate reactivities. These results disqualify pooling as a strategy for seroprevalence studies and screening programs.
No takes yet. Share an insight, caveat, or question.
Stephens et al. (2000) studied this question.
Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context: