Key result
Ischaemic heart disease during pregnancy occurs in 2.8 to 6.2 per 100,000 deliveries and is associated with high maternal morbidity due to heart failure, arrhythmia, and cardiogenic shock.
Why the study?
Ischaemic heart disease is becoming more common in pregnancy due to delayed childbearing, increasing comorbidities, and higher obesity rates, yet pregnancy-related mechanisms remain unclear.
Ischaemic heart disease in pregnancy is rare but increasing, requiring standard non-pregnant investigation protocols and obstetric-guided delivery.
Rising AMI rates in pregnancy require standard urgent evaluation; leaves open targeted prevention strategies pending higher-level evidence.
Although ischaemic heart disease is currently rarely encountered in pregnancy, occurring between 2.8 and 6.2 per 100 000 deliveries, it is becoming more common as women delay becoming pregnant until later life, when medical comorbidities are more common, and because of the higher prevalence of obesity in the pregnant population. In addition, chronic inflammatory diseases, which are more common in women, may contribute to greater rates of acute myocardial infarction (AMI). Pregnancy itself seems to be a risk factor for AMI, although the exact mechanisms are not clear. AMI in pregnancy should be investigated in the same manner as in the non-pregnant population, not allowing for delays, with investigations being conducted as they would outside of pregnancy. Maternal morbidity following AMI is high as a result of increased rates of heart failure, arrhythmia and cardiogenic shock. Delivery in women with history of AMI should be typically guided by obstetric indications not cardiac ones.
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Cauldwell et al. (2018) conducted a review in Ischaemic heart disease in pregnancy. Ischaemic heart disease during pregnancy occurs in 2.8 to 6.2 per 100,000 deliveries and is associated with high maternal morbidity due to heart failure, arrhythmia, and cardiogenic shock.
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