Key result
An 86-year-old female with COVID-19 developed severe Takotsubo cardiomyopathy and cardiogenic shock, ultimately passing away seven days after hospital admission despite targeted medical therapy.
Case Report (n=1)
No
COVID-19 can induce severe Takotsubo cardiomyopathy in geriatric patients, potentially leading to fatal cardiogenic shock despite aggressive medical and hemodynamic support.
Answers are grounded in this paper and cite their sources.
Case of COVID-19–triggered Takotsubo in frail elderly warrants consideration in differential; leaves open incidence, mechanisms, and management in larger cohorts.
An 86-year-old female with a past medical history of hypertension, vertebral fractures with chronic lumbar pain, hip fracture, osteoporosis, deafness, and microcytic anemia underwent hospital admission for emergency medical management of her respiratory distress. The (overall) diagnostic workup confirmed COVID-19, the patient presented with 50% SPO2 (oxygen saturation), sinus tachycardia, diffuse bilateral pulmonary crackles, mild jugular venous distention (JVD), minimal bilateral pitting edema, elevated cardiac enzymes, bilateral pulmonary opacities, and ST-segment elevation. The cardiovascular assessment indicated stress-induced cardiomyopathy/Takotsubo cardiomyopathy (TCM) determined by 35%-40% LVEF (left ventricular ejection fraction), mid to apical left ventricular (LV) akinesia with preserved function in the proximal segment, aortic valve sclerosis, reduced excursion of Trileaflet valve (without stenosis), and mild-to-moderate tricuspid regurgitation with moderate pulmonary artery systolic pressure (PASP). The treatment protocol relied on 81 mg aspirin, 75 mg plavix, 20 mg lipitor, remdesivir, dexamethasone, ceftriaxone, azithromycin, red blood cells transfusion (pRBCs), endotracheal intubation for respiratory support, and systemic hemodynamic support. The patient's condition did not improve despite all treatment, and she passed away after seven days following her hospital admission.
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Alshamam et al. (2021) conducted a case report in COVID-19-Induced Takotsubo Cardiomyopathy (n=1). COVID-19 was evaluated on Clinical outcome (mortality). An 86-year-old female with COVID-19 developed severe Takotsubo cardiomyopathy and cardiogenic shock, ultimately passing away seven days after hospital admission despite targeted medical therapy.
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