The blast cells from four patients with acute leukemia and Down’s syndrome were found to contain unusual inclusions which manifested similar morphologic and cytochemical characteristics. Ultrastructure studies of the blasts from one of these patients revealed the inclusions to be single membrane-bound structures containing electron-dense amorphous debris, membranous substance, and virus-like particles.
No takes yet. Share an insight, caveat, or question.
Brunning et al. (1974) studied this question.
Synapse has enriched 5 related papers. Consider them for comparative context: